The Food and Drug Administration (FDA) includes Ethylcellulose, Hydroxypropylcellulose, Methyl Ethylcellulose and Hydroxypropyl Methylcellulose on its list of multipurpose additives allowed to be directly added to food. FDA also permits Cellulose and a number of modified cellulose polymers to be used as indirect food additives. For example, Cellulose, Cellulose Acetate Butryate, Cellulose Acetate Propionate, Cellulose Gum, Hydroxyethylcellulose, Hydroxyethyl Ethylcellulose, Hydroxypropyl Methylcellulose and Methylcellulose can be used in adhesives in contact with food. As substances migrating to food from paper and paperboard products, FDA considers Cellulose Acetate and Ethylcellulose to be Generally Recognized as Safe (GRAS). The FDA has also approved the use of Cellulose Gum, Hydroxyethylcellulose, Hydroxypropyl Methylcellulose and Methylcellulose for use as ophthalmic demulcents in over-the-counter (OTC) drug products for the eyes.